My laptop is a Toshiba S75Dt-A7330. When any USB mouse is plugged in the screen won't turn off after the requested time. When the mouse is unplugged the screen turns off and when the mouse is then plugged in the screen automatically turns on. Is the problem fixable so that I don't have to unplug the mouse when I'm finished with the computer for a period of time?

What operating system? If it's 10 try

Start > Settings > Power & Sleep > Additional Power Settings > Change Plan Settings > Change Advanced Power Settings > USB Settings > USB Selective Suspend Setting > Set to Disabled

This doesn't work for everyone and it seems that it's various issues for different setups.

Thanks for your response. It is Windows 10 and I have tried that. No success. Have this same problem on several laptops different mouse connected.

Are these corded mice or wireless?

corded mice.

Have you tried wireless, I'm wondering if a USB dongle will trigger the same behavior with a mouse you can turn off. You might want to check your manufacturers site for bios updates. They also correct a lot of problems so you should keep it up to date.

Is it a Microsoft mouse?

I've switched to a wireless mouse with a USB dongle with success. So, thanks everyone.